Immunopathology of subcutaneous rheumatoid nodules.
نویسندگان
چکیده
منابع مشابه
Immunopathology of subcutaneous rheumatoid nodules.
Nodules obtained from five patients with classical seropositive rheumatoid arthritis were studied by an immunofluorescence technique using polyclonal antibodies to IgG, IgA, IgM, C3c, and fibrin, and monoclonal antibodies to the terminal (C5b-9) complement complex (reaction with a neoantigen in C9 revealed during activation), DR antigens, T cells, macrophages, and interdigitating cells. In all ...
متن کاملSubcutaneous Rheumatoid Nodules.
death to give reliable results. The postmortem interval as already defined established fixed limits for the interval and avoided possible overestimation of the amino acid concentration relative to time after death. Analysis of the results showed no evidence that a specific aminoacidopathy is implicated in the aetiology of cot death but has nevertheless improved our understanding of the biochemi...
متن کاملSubcutaneous rheumatoid nodules.
We describe seven children with subcutaneous rheumatoid nodules who had no clinical evidence of rheumatoid arthritis. Only one girl was seropositive for antinuclear factors and had a slightly raised erythrocyte sedimentation rate. Clinical aspects, risks for developing rheumatoid arthritis, and treatment of this entity are discussed.
متن کاملSubcutaneous nodules in rheumatoid arthritis.
A 29 year old male with rheumatoid arthritis (RA) of 10 years duration presented with multiple subcutaneous nodules of one month duration while on methotrexate (7.5 mg once a week), salazopyrine (1000 mg/day) and methyl prednisolone (4 mg/day). The nodules involved tendons of metacarpophalangeal joints (Figure 1) and base of left great toe (Figure 2), were painless and did not interfere with hi...
متن کاملThe significance of subcutaneous nodules in rheumatoid arthritis.
The presence of subcutaneous nodules in rheumatic fever is of serious prognostic significance because, as they are pathologically similar to the Aschoff bodies found in the heart, they generally indicate severe cardiac damage and active infection. As a rule nodules appear after the onset of the rheumatic heart lesion. There is, therefore, practically always cardiac involvement in cases where no...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1991
ISSN: 0003-4967
DOI: 10.1136/ard.50.12.909